Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

Impaired kidney development in Wnt4^tm1.1Svo/Wnt4^tm1.1Svo Tg(CAG-cre)13Miya/0 (Wnt4^c/c;CAGCre) fetuses. The urogenital system of E17.5 wild-type and Wnt4^tm1.1Svo/Wnt4^tm1.1Svo Tg(CAG-cre)13Miya/0 embryos, indicating pairs of kidneys, the adrenal gland, and the ovary. Early inactivation of Wnt4 function with CAGCre impairs kidney development and the kidneys remain rudimentary. Labels: a, adrenal gland; b, bladder; g, gonad; k, kidney. (b) Bar 100 uM.

This image is from Shan J, Genesis 2009 Nov;47(11):782-8, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:154784

Associated
Alleles

Symbol	Name
Tg(CAG-cre)13Miya	transgene insertion 13, Jun-ichi Miyazaki
Wnt4^tm1.1Svo	wingless-type MMTV integration site family, member 4; targeted mutation 1.1, Seppo Vainio

Associated
Genotypes

Allelic Composition	Genetic Background
Wnt4^tm1.1Svo/Wnt4^tm1.1Svo Tg(CAG-cre)13Miya/0	involves: 129/Sv * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24