Phenotype Image Detail

Image

Caption

Morphometric analysis of islet size. Representative sections of pancreas immunostained with anti-beta catenin antibody to visual beta cell and islet size in Rps6kb1^tm1Gtho/Rps6kb1^tm1Gtho (S6K1-/-), Tg(Ins2-Akt1*)3Mbb/0 (MyrAkt1), and Tg(Ins2-Akt1*)3Mbb/0 Rps6kb1^tm1Gtho/Rps6kb1^tm1Gtho (MyrAkt1;S6K1-/-) mice.

This image is from Alliouachene S, J Clin Invest 2008 Nov;118(11):3629-38 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144599

Associated
Alleles

Symbol	Name
Rps6kb1^tm1Gtho	ribosomal protein S6 kinase, polypeptide 1; targeted mutation 1, George Thomas
Tg(Ins2-Akt1*)3Mbb	transgene insertion 3, Morris J Birnbaum

Associated
Genotypes

Allelic Composition	Genetic Background
Rps6kb1^tm1Gtho/Rps6kb1^tm1Gtho	B6.129P2-Rps6kb1^tm1Gtho
Tg(Ins2-Akt1*)3Mbb/0	B6.Cg-Tg(Ins2-Akt1*)3Mbb
Rps6kb1^tm1Gtho/Rps6kb1^tm1Gtho Tg(Ins2-Akt1*)3Mbb/0	B6.Cg-Rps6kb1^tm1Gtho Tg(Ins2-Akt1*)3Mbb

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24