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Phenotype Image Detail
Image
Caption Morphometric analysis of islet size. Representative sections of pancreas immunostained with anti-beta catenin antibody to visual beta cell and islet size in Rps6kb1tm1Gtho/Rps6kb1tm1Gtho (S6K1-/-), Tg(Ins2-Akt1*)3Mbb/0 (MyrAkt1), and Tg(Ins2-Akt1*)3Mbb/0 Rps6kb1tm1Gtho/Rps6kb1tm1Gtho (MyrAkt1;S6K1-/-) mice.
Copyright This image is from Alliouachene S, J Clin Invest 2008 Nov;118(11):3629-38 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144599
Associated
Alleles
Symbol Name
Rps6kb1tm1Gtho ribosomal protein S6 kinase, polypeptide 1; targeted mutation 1, George Thomas
Tg(Ins2-Akt1*)3Mbb transgene insertion 3, Morris J Birnbaum
Associated
Genotypes
Allelic Composition Genetic Background
Rps6kb1tm1Gtho/Rps6kb1tm1Gtho B6.129P2-Rps6kb1tm1Gtho
Tg(Ins2-Akt1*)3Mbb/0 B6.Cg-Tg(Ins2-Akt1*)3Mbb
Rps6kb1tm1Gtho/Rps6kb1tm1Gtho
Tg(Ins2-Akt1*)3Mbb/0
B6.Cg-Rps6kb1tm1Gtho Tg(Ins2-Akt1*)3Mbb

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory