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Phenotype Image Detail
Image
Caption Cochlear innervation defects in Slitrk6tm1.1Jaru/Slitrk6tm1.1Jaru (-/-) mice. DiI-traced afferent innervation of apical (A, B) and basal (C, D) turns of the neonatal (P0) cochlea in wild-type (WT) (A, C) and mutant (B, D) mice. Mutant inner ear displays a marked alteration in the spacing of radial fibers in the cochlear innervation (B, D). Innervation defects are distributed evenly throughout the cochlea with no basal-to-apical gradient. DiI-labeled efferent innervation of the cochlear middle turn of WT (E) and mutant (F) neonatal mice. Efferent fibers show abnormalities similar to those noted for the afferent innervation. IGSB, intraganglionic spiral bundle; SG, spiral ganglion. Scale bars, 100 um.
Copyright This image is from Katayama K, PLoS One 2009;4(11):e7786, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155405
Associated
Alleles
Symbol Name
Slitrk6tm1.1Jaru SLIT and NTRK-like family, member 6; targeted mutation 1.1, Jun Aruga
Associated
Genotypes
Allelic Composition Genetic Background
Slitrk6tm1.1Jaru/Slitrk6tm1.1Jaru B6.129P2-Slitrk6tm1.1Jaru

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory