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Phenotype Image Detail
Image
Caption Progressive retinal degeneration in Rhotm1.1Kpal/Rho+ (P23H/+) mice. A, plastic sections of retinas from wild-type (WT), heterozygous (P23H/+), and homozygous (P23H/P23H) mice of differing postnatal day (PND) ages. Sections were stained with toluidine blue. OS, outer segment; IS, inner segment; ONL, outer nuclear layer; INL, inner nuclear layer; and GC/NFL, ganglion cell/nerve fiber layer. Arrows represent surviving rod nuclei in a homozygous P23H/P23H mouse.
Copyright This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648
Associated
Alleles
Symbol Name
Rhotm1.1Kpal rhodopsin; targeted mutation 1.1, Krzysztof Palczewski
Associated
Genotypes
Allelic Composition Genetic Background
Rhotm1.1Kpal/Rho+ involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Rhotm1.1Kpal/Rhotm1.1Kpal involves: 129S6/SvEvTac * C57BL/6 * FVB/N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory