Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Phenotype of Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} (Casz1^{betageo/betageo}) fetus and heart at E16.5. A, E16.5 mutant fetus shows evidence of edema and broad areas devoid of blood (green arrow). B, the E16.5 mutant hearts were morphologically different compared with wild type (Casz1^+/+) heart (compare the regions targeted by the yellow arrows). (Note the lack of blood in the mutant heart occurred after surgery.)

This image is from Liu Z, J Biol Chem 2014 Oct 24;289(43):29801-16 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:242127

Associated
Alleles

Symbol	Name
Casz1^{Gt(CJ0565)Wtsi}	castor zinc finger 1; gene trap CJ0565, Wellcome Trust Sanger Institute

Associated
Genotypes

Allelic Composition	Genetic Background
Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi}	involves: 129P2/OlaHsd * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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