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Caption | Appearance of wild-type (FAK+/+) and Ptk2tm1Heen/Ptk2tm1Heen (FAKdelta/delta) embryos at E13.5 and E15.5 (arrows, hemorrhages; arrowheads, edemas). Gross morphology defects of E14.5 wild-type and mutant lungs, heart, and liver (scale bars, 1 mm). E14.5 (upper panel) and E15.5 (lower panel) anterior (left) and posterior (right) footplates (scale bars, 1 mm). D, Mutant embryos show delayed artery formation and vascular remodeling defects. Whole-mount triple immunofluorescence confocal microscopy using antibodies to smooth muscle actin (SMA, green), PECAM1 (red), and neurons (TUJ1) (blue) on skin from E14.5 embryos. Confocal microscopy images were acquired using X10 magnification. | ||||
Copyright | This image is from Corsi JM, J Biol Chem 2009 Dec 11;284(50):34769-76 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:157804 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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