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| Caption | Olfactory sensory neurons axon targeting is perturbed in Ttc8tm1Reed/Ttc8tm1Reed (BBS8-/-) mice. The olfactory receptor reporter line M72TL, Or8a1btm4Mom, was crossed into a Ttc8tm1Reed/Ttc8tm1Reed background and axon targeting was analyzed by whole-mount X-Gal staining of PD15 mice. In dorsal views, axons project from the olfactory epithelium (OE) (on the bottom) to their targets in the olfactory bulb (OB). In wild-type (WT) mice, M72-tau:lacZ-expressing axons converge to one dorsal glomerulus in each bulb. In the OB of Ttc8tm1Reed/Ttc8tm1Reed mice, multiple glomeruli are innervated and individual fibers wander on the surface of the bulb. | ||||||
| Copyright | This image is from Tadenev AL, Proc Natl Acad Sci U S A 2011 Jun 21;108(25):10320-5. Copyright 2011 National Academy of Sciences, U.S.A. J:173465 | ||||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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