Phenotype Image Detail

Image

Caption

Slc3a2^tm1.1Merl/Slc3a2⁺ Tg(Vil1-cre)997Gum/0 mice are protected from dextran sodium sulfate (DSS)-induced colitis. Mice were administered regular water (control) or 3% DSS for 9 days. (B) Colon length of control (CD98^fl/+) and Slc3a2^tm1.1Merl/Slc3a2⁺ Tg(Vil1-cre)997Gum/0 (CD98^fl/+ VilCre) mice, measured at day 9 after treatment. (C) Representative H&E stained distal colonic sections and histological score, assessed at the end of DSS treatment. Scale bars: 100 um.

This image is from Nguyen HT, J Clin Invest 2011 May 2;121(5):1733-47 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173946

Associated
Alleles

Symbol	Name
Slc3a2^tm1.1Merl	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; targeted mutation 1.1, Didier Merlin
Tg(Vil1-cre)997Gum	transgene insertion 997, Deborah L Gumucio

Associated
Genotypes

Allelic Composition	Genetic Background
Slc3a2^tm1.1Merl/Slc3a2⁺ Tg(Vil1-cre)997Gum/0	B6.Cg-Slc3a2^tm1.1Merl Tg(Vil1-cre)997Gum

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