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Phenotype Image Detail
Image
Caption Analysis of livers in mice with heterozygous and homozygous Fbxw7tm1.1Iken mutations. (A-C) Representative H&E staining of the livers of control (+/+) (A), Alb-Cre;Fbxw7LSL-R468C/+ (Fbxw7Hep-R468C/+;Hep-R468C/+) (B), and Alb-Cre;Fbxw7LSL-R468C/LSL-R468C (Fbxw7Hep-R468C/Hep-R468C;Hep-R468C/Hep-R468C) (C) mice at 12 months of age. Bar, 100 um. (D) Expression of Fbxw7 substrates in the livers of mice with the indicated genotype
Copyright This image is from Ikenoue T, Sci Rep 2018 Jan 31;8(1):2021, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:258194
Associated
Alleles
Symbol Name
Fbxw7tm1Iken F-box and WD-40 domain protein 7; targeted mutation 1, Tsuneo Ikenoue
Speer6-ps1Tg(Alb-cre)21Mgn spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory