Phenotype Image Detail

Image

Caption

Absence of melanocytes or pigment in hair follicles of Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Tyr-cre)1Lru/Y Tg(Dct-lacZ)A12Jkn/0 mice at the anagen phase of the second hair cycle. XGal stain of whole-mount skin sections from P38 Tg(Tyr-cre)1Lru/Y Yy1^tm2.1Yshi/Yy1⁺ Tg(Dct-lacZ)A12Jkn/0 (TyrCre, yy1^f/+) (K) and Tg(Tyr-cre)1Lru/Y Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Dct-lacZ)A12Jkn/0 (TyrCre, yy1^f/f) (L) mice.

This image is from Li J, PLoS Genet 2012 May;8(5):e1002688, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185128

Associated
Alleles

Symbol	Name
Tg(Dct-lacZ)A12Jkn	transgene insertion A12, Ian Jackson
Tg(Tyr-cre)1Lru	transgene insertion 1, Lionel Larue
Yy1^tm2.1Yshi	YY1 transcription factor; targeted mutation 2.1, Yang Shi

Associated
Genotypes

Allelic Composition	Genetic Background
Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Dct-lacZ)A12Jkn/0 Tg(Tyr-cre)1Lru/Y	involves: 129S4/SvJae * C57BL/6 * CBA * DBA/2

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24