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Phenotype Image Detail
Image
Caption Representative testes, seminal vesicles, and uteri from wild-type (p57WT), Cdkn1ctm1Kat/Cdkn1c+ (p57KO), and Cdkn1ctm1.1(Cdkn1b*)Kei/Cdkn1c+ (p57p27KI) mice at 7 weeks of age. Tissues of each pair were from littermates. Sections of the uterus were also subjected to hematoxylin-eosin staining; the muscle layer of the p57KO uterus was thinner than that of the p57WT or p57p27KI uteri (arrows). (Scale bars: macroscopic comparisons, 5 mm; uterine sections, 50 um.) (E) Vaginal atresia (arrowhead) of a p57KO mouse at 7 weeks of age, and its correction in a p57p27KI mouse.
Copyright This image is from Susaki E, Proc Natl Acad Sci U S A 2009 Mar 31;106(13):5192-7. Copyright 2009 National Academy of Sciences, U.S.A. J:147145
Associated
Alleles
Symbol Name
Cdkn1ctm1.1(Cdkn1b*)Kei cyclin dependent kinase inhibitor 1C; targeted mutation 1.1, Keiichi I Nakayama
Cdkn1ctm1Kat cyclin dependent kinase inhibitor 1C; targeted mutation 1, Katsuhiko Takahashi
Associated
Genotypes
Allelic Composition Genetic Background
Cdkn1ctm1.1(Cdkn1b*)Kei/Cdkn1c+ involves: 129P2/OlaHsd * C57BL/6J
Cdkn1ctm1Kat/Cdkn1c+ involves: 129P2/OlaHsd * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory