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Phenotype Image Detail
Image
Caption Impact of DREC deletion on dioxin-induced toxicity. (D and E) MGI:3840320/MGI:3840320 (DREC-/-) mice were given a single injection of DMSO or 64 ug/kg of dioxin and were killed 5 days later. Liver sections were stained with H&E and immunostained with F4/80 antibody. (D) H&E. The black arrowhead indicates the region of hydropic degeneration; * indicates focal inflammation. (Magnification: X100.) (a) WT given dioxin. (Magnification: X400.) (b) MGI:3840320/MGI:3840320 (DREC-/-) given dioxin. (Magnification: X400.) (E) F4/80. The brown spots indicate F4/80-positive cells. (Magnification: X100.)
Copyright This image is from Nukaya M, Proc Natl Acad Sci U S A 2009 Mar 24;106(12):4923-8. Copyright 2009 National Academy of Sciences, U.S.A. J:147150
Associated
Alleles
Symbol Name
Cyp1atm1.1Bra cytochrome P450, family 1, subfamily a cluster; targeted mutation 1.1, Christopher A Bradfield
Associated
Genotypes
Allelic Composition Genetic Background
Cyp1atm1.1Bra/Cyp1atm1.1Bra B6.129-Cyp1atm1.1Bra

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory