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Phenotype Image Detail
Image
Caption Cd300lbtm1Toki/Cd300lbtm1Toki mice were protected from renal ischemia reperfusion injury (IRI). 6(C and D) Tubular injury (C) or neutrophil accumulation within the interstitium in IRI kidneys (D) of wild-type (WT) and mutant mice at 24 h after surgery. Representative sections of the outer and inner medulla from contralateral or IRI kidneys from WT and mutant mice at 24 h after surgery. (C) Hematoxylin and eosin staining. Bars, 100 um. (D) Immunohistochemical identification of neutrophils (brown) in the outer and inner medulla (top and bottom, respectively). Immunohistochemical identification of neutrophils (green) in the outer medulla (middle). The nuclei were counterstained with DAPI (blue). Bars, 100 um. (E) Neutrophil counts of 10 high-power fields (HPFs) from each section from the outer medulla. Data shown are means SD (n = 8 mice in each group). Statistically significant differences are shown. *, P<0.05. Three independent experiments were performed in C, D & E.
Copyright This image is from Yamanishi Y, J Exp Med 2010 Jul 5;207(7):1501-11, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:163402
Associated
Alleles
Symbol Name
Cd300lbtm1Toki CD300 molecule like family member B; targeted mutation 1, Toshio Kitamura
Associated
Genotypes
Allelic Composition Genetic Background
Cd300lbtm1Toki/Cd300lbtm1Toki B6.Cg-Cd300lbtm1Toki

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory