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| Caption | IL-33 is required for development of an IgE/mast cell independent OVA-induced allergic airway hypersensitivity response. Wild-type (IL-33+/+) and Il33tm1Snak/Il33tm1Snak (IL-33-/-) mice were sensitized twice with OVA emulsified in alumon days 0 and 14. The mice were challenged intranasally with OVA or saline alone on days 28, 29, and 30. Lung sections stained with hematoxylin-eosin (C) (100X representative data from three to five mice are shown) at 24 hours after the last OVA or PBS inhalation. Data show the mean SE: *P < 0.05 vs. corresponding values for saline-treated mice; P < 0.05 vs. OVA-treated mutant mice. | ||||
| Copyright | This image is from Oboki K, Proc Natl Acad Sci U S A 2010 Oct 26;107(43):18581-6. Copyright 2010 National Academy of Sciences, U.S.A. J:165513 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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