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Phenotype Image Detail
Image
Caption The rd25/rd25 retinal phenotypes in fundus, OCT, histology, and ERG. Homozygous mice exhibit a normal retina at 3 months of age (A) and begin to show retinal degeneration at 5 months of age (B) in OCT. Histology and OCT at 10 months of age showed about 30-40% photoreceptor loss. Electroretinograms (ERG) shows normal rod ERG responses at 3 months of age, abnormal rod ERG responses (lower ERG) at 5 and 10 months of age, but the cone ERG responses were not much changed within the same time frame (Right panel ERGs).
Copyright Photo courtesy of Mouse Mutant Resource at The Jackson Laboratory. J:349874
Associated
Alleles
Symbol Name
rd25 retinal degeneration 25
Associated
Genotypes
Allelic Composition Genetic Background
rd25/rd25 B6.Cg-rd25/BocJ

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory