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Caption | The rd25/rd25 retinal phenotypes in fundus, OCT, histology, and ERG. Homozygous mice exhibit a normal retina at 3 months of age (A) and begin to show retinal degeneration at 5 months of age (B) in OCT. Histology and OCT at 10 months of age showed about 30-40% photoreceptor loss. Electroretinograms (ERG) shows normal rod ERG responses at 3 months of age, abnormal rod ERG responses (lower ERG) at 5 and 10 months of age, but the cone ERG responses were not much changed within the same time frame (Right panel ERGs). | ||||
Copyright | Photo courtesy of Mouse Mutant Resource at The Jackson Laboratory. J:349874 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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