Phenotype Image Detail

Image

Caption

Representative images: A) Rpe65^tm1Tmr/Rpe65^tm1Tmr [B6.129-Rpe65^tm1Tmr/Boc] with white retinal spots and retinal degeneration at 3 months of age, B) Rpe65^tm1Tmr/Rpe65^tm1Tmr mice with more retinal white spots and retinal degeneration at 5 months of age, C) Rpe65^rd12/ Rpe65^rd12 [B6(A)-Rpe65^rd12/J] with more white retinal spots and retinal degeneration at 5 months of age and D) C57BL/6J control at 5 months of age using an in vivo bright field retinal imaging microscope equipped with image-guided OCT capabilities (Micron III; Phoenix Laboratories, Inc., Pleasanton, CA, USA). The green lines are the plane in which the B-scan to the bottom of the fundus images were taken in the same animal.

Photo courtesy of Mouse Mutant Resource at The Jackson Laboratory. J:348118

Associated
Alleles

Symbol	Name
Rpe65^rd12	retinal pigment epithelium 65; retinal degeneration 12
Rpe65^tm1Tmr	retinal pigment epithelium 65; targeted mutation 1, T Michael Redmond

Associated
Genotypes

Allelic Composition	Genetic Background
Rpe65^rd12/Rpe65^rd12	B6(A)-Rpe65^rd12/J
Rpe65^tm1Tmr/Rpe65^tm1Tmr	B6.129-Rpe65^tm1Tmr/BocJ

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24