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Phenotype Image Detail
Image
Caption Ccdc59em1(IMPC)J/Ccdc59em1(IMPC)J mutants can be recovered at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has not formed, and no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates fairly wide-spread expression with notable absence in blastocysts and yolk sac at E8.5. Mutants appear as a necotic mass of cells at E7.5. Additional information at websites.umass.edu/jmager/Ccdc59
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ccdc59em1(IMPC)J coiled-coil domain containing 59; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Ccdc59em1(IMPC)J/Ccdc59em1(IMPC)J C57BL/6NJ-Ccdc59em1(IMPC)J/J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory