About   Help   FAQ
Phenotype Image Detail
Image
Caption Ccdc59em1(IMPC)J/Ccdc59em1(IMPC)J mutants can be recovered at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has not formed, and no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates fairly wide-spread expression with notable absence in blastocysts and yolk sac at E8.5. Mutants appear as a necotic mass of cells at E7.5. Additional information at websites.umass.edu/jmager/Ccdc59
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ccdc59em1(IMPC)J coiled-coil domain containing 59; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Ccdc59em1(IMPC)J/Ccdc59em1(IMPC)J C57BL/6NJ-Ccdc59em1(IMPC)J/J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory