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Phenotype Image Detail
Image
Caption Cherpem1(IMPC)J/Cherpem1(IMPC)J embryos cannot be recovered at E7.5 (0/32), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and appear as irregular morula or early blastocysts. Mutants hatch from the zona pellucida and form outgrowths with no defined inner cell mass and few trophectoderm cells. RNA-seq data indicates robust zygotic and 8-cell expression. Additional information at websites.umass.edu/jmager/Cherp
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Cherpem1(IMPC)J calcium homeostasis endoplasmic reticulum protein; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Cherpem1(IMPC)J/Cherpem1(IMPC)J C57BL/6NJ-Cherpem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory