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Phenotype Image Detail
Image
Caption Eif5bem1(IMPC)J/Eif5bem1(IMPC)J embryos cannot be recovered at E7.5 (0/29), nor are there excess resorption sites. Homozygous mutants are recovered at lower than expected ratios at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming blastocysts. RNA-seq data indicates robust maternal and zygotic expression. Additional information at websites.umass.edu/jmager/Eif5b
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Eif5bem1(IMPC)J eukaryotic translation initiation factor 5B; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Eif5bem1(IMPC)J/Eif5bem1(IMPC)J C57BL/6NJ-Eif5bem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory