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Phenotype Image Detail
Image
Caption Ltv1em1(IMPC)J/Ltv1em1(IMPC)J embryos cannot be recovered at E7.5 (0/20), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming blastocysts. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Ltv1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ltv1em1(IMPC)J LTV1 ribosome biogenesis factor; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Ltv1em1(IMPC)J/Ltv1em1(IMPC)J C57BL/6NJ-Ltv1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory