Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Mrps25^{tm1.1(KOMP)Vlcg}/Mrps25^{tm1.1(KOMP)Vlcg} are recovered at expected Mendelian ratios at E7.5. Mutants show consistent phenotype including developmental delay (~E6.0 size), poorly organized extraembryonic tissues, and no Brachyury (T)-positive cells. Phospho-histoneH3 staining shows many dividing cells despite the overall developmental delay. RT-PCR and LacZ show largely ubiquitous expression. Additional information at websites.umass.edu/jmager/Mrps25

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Mrps25^{tm1.1(KOMP)Vlcg}	mitochondrial ribosomal protein S25; targeted mutation 1.1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Mrps25^{tm1.1(KOMP)Vlcg}/Mrps25^{tm1.1(KOMP)Vlcg}	C57BL/6N-Mrps25^{tm1.1(KOMP)Vlcg}/JMmucd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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