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Phenotype Image Detail
Image
Caption Cenpotm1b(KOMP)Mbp/Cenpotm1b(KOMP)Mbp mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates robust expression in gastrulation stages. Weak LacZ reporter expression. Additional information at websites.umass.edu/jmager/Cenpo
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Cenpotm1b(KOMP)Mbp centromere protein O; targeted mutation 1b, Mouse Biology Program, UC Davis
Associated
Genotypes
Allelic Composition Genetic Background
Cenpotm1b(KOMP)Mbp/Cenpotm1b(KOMP)Mbp B6N(Cg)-Cenpotm1b(KOMP)Mbp/J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory