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Phenotype Image Detail
Image
Caption Ska2tm1b(KOMP)Wtsi/Ska2tm1b(KOMP)Wtsi mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates robust wide-spread expression. No knock-in LacZ reporter staining is observed in E6.5, E7.5 or E8.5 embryos (not shown). Additional information at websites.umass.edu/jmager/Ska2
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ska2tm1b(KOMP)Wtsi spindle and kinetochore associated complex subunit 2; targeted mutation 1b, Wellcome Trust Sanger Institute
Associated
Genotypes
Allelic Composition Genetic Background
Ska2tm1b(KOMP)Wtsi/Ska2tm1b(KOMP)Wtsi B6N(Cg)-Ska2tm1b(KOMP)Wtsi/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory