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Phenotype Image Detail
Image
Caption Ppp1r35tm1.1(KOMP)Vlcg/Ppp1r35tm1.1(KOMP)Vlcg are recovered at Mendelian ratios at E7.5-E9.5. Mutants show consistent phenotype including developmental delay, failure to turn, ballooning pericardial sac and neural tube cell death. Both RT-PCR and knock-in LacZ reporter indicate wide-spread expression at post-implantation stages with notable absence in endoderm (VE and PE). Additional information at websites.umass.edu/jmager/Ppp1r35
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ppp1r35tm1.1(KOMP)Vlcg protein phosphatase 1, regulatory subunit 35; targeted mutation 1.1, Velocigene
Associated
Genotypes
Allelic Composition Genetic Background
Ppp1r35tm1.1(KOMP)Vlcg/Ppp1r35tm1.1(KOMP)Vlcg B6N(Cg)-Ppp1r35tm1.1(KOMP)Vlcg/J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory