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Phenotype Image Detail
Image
Caption Rbbp4em1(IMPC)Mbp/Rbbp4em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/43), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 and appear as normal blastocysts. Mutants hatch from the zona but fail to form typical outgrowth colonies. RT-PCR indicates limited early expression during pre-implantation and robust post-implantation expression. Additional information at websites.umass.edu/jmager/Rbbp4
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Rbbp4em1(IMPC)Mbp retinoblastoma binding protein 4, chromatin remodeling factor; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Associated
Genotypes
Allelic Composition Genetic Background
Rbbp4em1(IMPC)Mbp/Rbbp4em1(IMPC)Mbp C57BL/6NCrl-Rbbp4em1(IMPC)Mbp/Mmucd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory