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Phenotype Image Detail
Image
Caption Zwintem1(IMPC)J/Zwintem1(IMPC)J embryos cannot be recovered at E7.5 (0/28) with an excess number of resorption sites (10). Homozygous mutants are recovered at E3.5 in expected ratios and appear as normal blastocysts. Mutants hatch from the zona with apparent trophectoderm and primitive endoderm cells, but the inner cell mass/epiblast cells form a smaller than normal outgrowth colony. RT-PCR indicates expression during all stages examined in pre- and post-implantation. Additional information at websites.umass.edu/jmager/Zwint
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Zwintem1(IMPC)J ZW10 interactor; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Zwintem1(IMPC)J/Zwintem1(IMPC)J C57BL/6NJ-Zwintem1(IMPC)J/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory