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Phenotype Image Detail
Image
Caption Orc6em1(IMPC)J/Orc6em1(IMPC)J embryos cannot be recovered at E7.5 (0/34), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 in expected ratios and appear as dying morula. Mutants fail to hatch from the zona with apparent cell death, never reaching a morphological blastocyst stage. RT-PCR indicates robust expression both pre-implantationand post-implantation stages examined. Additional information at websites.umass.edu/jmager/Orc6
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Orc6em1(IMPC)J origin recognition complex, subunit 6; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Orc6em1(IMPC)J/Orc6em1(IMPC)J C57BL/6NJ-Orc6em1(IMPC)J/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory