Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Borcs6^{tm1.1(KOMP)Vlcg}/Borcs6^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has formed at E6.5 but degenerated by E7.5. No morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates robust expression post E6.5. Weak knock-in LacZ reporter expression at all stages. Additional information at websites.umass.edu/jmager/Borcs6

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Borcs6^{tm1.1(KOMP)Vlcg}	BLOC-1 related complex subunit 6; targeted mutation 1.1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Borcs6^{tm1.1(KOMP)Vlcg}/Borcs6^{tm1.1(KOMP)Vlcg}	B6N(Cg)-Borcs6^{tm1.1(KOMP)Vlcg}/J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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