Phenotype Image Detail

Image

Caption

Mrps18c^{tm1.1(KOMP)Vlcg}/Mrps18c^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. No Brachyury (T)-positive cells are present at E7.5. RT-PCR indicates expression in all stages. Robust LacZ knock-in expression is observed at all stages. Additional information at websites.umass.edu/jmager/Mrps18c

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Mrps18c^{tm1.1(KOMP)Vlcg}	mitochondrial ribosomal protein S18C; targeted mutation 1.1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Mrps18c^{tm1.1(KOMP)Vlcg}/Mrps18c^{tm1.1(KOMP)Vlcg}	C57BL/6N-Mrps18c^{tm1.1(KOMP)Vlcg}/JMmucd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24