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Phenotype Image Detail
Image
Caption Trit1tm1.1(KOMP)Vlcg/Trit1tm1.1(KOMP)Vlcg embryos cannot be recovered at the expected ratio at E7.5 (3/43). Though an egg cyclinder is formed, no morphological node or other hallmarks typical of E7.5 (i.e. headfolds) are present. Homozygous mutants are recovered at E3.5 in expected ratios and appear as normal blastocysts. Mutants hatch from the zona and form fairly normal outgrowth colonies. RT-PCR indicates limited expression during preimplantation but robust post-implantation expression. Knock-in LacZ indicates neural tube expression at E8.5 (no expression at E6.5 or E7.5). Additional information at websites.umass.edu/jmager/Trit1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Trit1tm1.1(KOMP)Vlcg tRNA isopentenyltransferase 1; targeted mutation 1.1, Velocigene
Associated
Genotypes
Allelic Composition Genetic Background
Trit1tm1.1(KOMP)Vlcg/Trit1tm1.1(KOMP)Vlcg C57BL/6N-Trit1tm1.1(KOMP)Vlcg/JMmucd

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory