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Phenotype Image Detail
Image
Caption Prim1em1(IMPC)J/ Prim1em1(IMPC)J embryos cannot be recovered at E7.5 (0/24), with some excess resorption sites. Homozygous mutants are recovered at ratios at E3.5 and appear as normal blastocysts. Mutants hatch from the zona and form outgrowths with apparent inner cell mass but limited/no trophectoderm or primitive endoderm cells. RT-PCR indicates robust maternal and post-implantation expression. Additional information at websites.umass.edu/jmager/Prim1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Prim1em1(IMPC)J DNA primase, p49 subunit; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Prim1em1(IMPC)J/Prim1em1(IMPC)J C57BL/6NJ-Prim1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory