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Phenotype Image Detail
Image
Caption Nsl1em1(IMPC)J/Nsl1em1(IMPC)J embryos cannot be recovered at E7.5 (0/27), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming blastocysts. RNA-seq data indicates robust expression. Additional information at websites.umass.edu/jmager/Nsl1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Nsl1em1(IMPC)J NSL1, MIS12 kinetochore complex component; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Nsl1em1(IMPC)J/Nsl1em1(IMPC)J C57BL/6NJ-Nsl1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory