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Phenotype Image Detail
Image
Caption Ndc80em1(IMPC)J/Ndc80em1(IMPC)J embryos cannot be recovered at E7.5 (0/29), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as early blastocysts. Mutants fail to hatch from the zona and are dead after 72 hours in culture. RNA-seq data indicates robust maternal and zygotic expression. Additional information at websites.umass.edu/jmager/Ndc80
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ndc80em1(IMPC)J NDC80 kinetochore complex component; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Ndc80em1(IMPC)J/Ndc80em1(IMPC)J C57BL/6NJ-Ndc80em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory