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Phenotype Image Detail
Image
Caption Tbccem1(IMPC)J/Tbccem1(IMPC)J embryos cannot be recovered at E7.5 (0/25), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and are blastocysts. Mutants hatch from the zona and form outgrowths with apparent trophectoderm cells but limited/no inner cell mass. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/Tbcc
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Tbccem1(IMPC)J tubulin-specific chaperone C; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Tbccem1(IMPC)J/Tbccem1(IMPC)J C57BL/6NJ-Tbccem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory