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Phenotype Image Detail
Image
Caption U2af2em1(IMPC)J/U2af2em1(IMPC)J embryos cannot be recovered at E7.5 (0/38), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 as early blastocysts. Mutants fail to hatch from the zona and are dead after 72 hr in vitro outgrowth culture. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/U2af2
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
U2af2em1(IMPC)J U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
U2af2em1(IMPC)J/U2af2em1(IMPC)J C57BL/6NJ-U2af2em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory