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Phenotype Image Detail
Image
Caption Tsen54em1(IMPC)J/Tsen54em1(IMPC)J embryos cannot be recovered at E7.5 (0/32), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72 hr in vitro outgrowth culture. RNA-seq data indicates robust maternal and embryonic expression. Additional information at websites.umass.edu/jmager/Tsen54
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Tsen54em1(IMPC)J tRNA splicing endonuclease subunit 54; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Tsen54em1(IMPC)J/Tsen54em1(IMPC)J C57BL/6NJ-Tsen54em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory