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Phenotype Image Detail
Image
Caption Nifkem1(IMPC)Mbp/Nifkem1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/30), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 and appear as dying morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming outgrowths. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Nifk
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Nifkem1(IMPC)Mbp nucleolar protein interacting with the FHA domain of MKI67; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Associated
Genotypes
Allelic Composition Genetic Background
Nifkem1(IMPC)Mbp/Nifkem1(IMPC)Mbp C57BL/6NCrl-Nifkem1(IMPC)Mbp/Mmucd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory