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Phenotype Image Detail
Image
Caption Taf12em1(IMPC)Mbp/Taf12em1(IMPC)Mbp mutants can be recovered at E3.5 but not at E7.5. Mutant embryos are able to form morphologically normal blastocysts, but outgrowths lack an obvious inner call mass colony. Mutant blastocysts exhibit comparable SOX17+ and NANOG+ cells. RT-PCR showed robust expression of Cdx2, Nanog and Oct4 in mutant blastocysts. Additional information at websites.umass.edu/jmager/Taf12
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Taf12em1(IMPC)Mbp TATA-box binding protein associated factor 12; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Associated
Genotypes
Allelic Composition Genetic Background
Taf12em1(IMPC)Mbp/Taf12em1(IMPC)Mbp C57BL/6NCrl-Taf12em1(IMPC)Mbp/Mmucd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory