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Phenotype Image Detail
Image
Caption Ttc1em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/27), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as blastocysts. Mutants hatch from the zona and form irregular outgrowths with poorly defined inner cell mass colony. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Ttc1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ttc1em1(IMPC)Mbp tetratricopeptide repeat domain 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Associated
Genotypes
Allelic Composition Genetic Background
Ttc1em1(IMPC)Mbp/Ttc1em1(IMPC)Mbp C57BL/6NCrl-Ttc1em1(IMPC)Mbp/Mmucd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory