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Phenotype Image Detail
Image
Caption Nup54em1(IMPC)Bay/Nup54em1(IMPC)Bay are recovered at expected Mendelian ratios at E7.5. Mutants show consistent phenotype including severe developmental delay as small egg cylinders, poorly organized extraembryonic tissues, and no Brachyury (T)-positive cells. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/NUP54
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Nup54em1(IMPC)Bay nucleoporin 54; endonuclease-mediated mutation 1, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Nup54em1(IMPC)Bay/Nup54em1(IMPC)Bay C57BL/6NJ-Nup54em1(IMPC)Bay/Mmnc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory