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Phenotype Image Detail
Image
Caption Ticrrem1(IMPC)Bay/Ticrrem1(IMPC)Bay embryos cannot be recovered at E7.5 (0/37), nor are there excess reabsorption sites. Homozygous mutants are recovered at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming outgrowths. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Ticrr
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Ticrrem1(IMPC)Bay TOPBP1-interacting checkpoint and replication regulator; endonuclease-mediated mutation 1, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Ticrrem1(IMPC)Bay/Ticrrem1(IMPC)Bay C57BL/6NJ-Ticrrem1(IMPC)Bay/Mmnc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory