Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Ranbp2^{tm1.1(KOMP)Vlcg}/Ranbp2^{tm1.1(KOMP)Vlcg} embryos cannot be recovered at E7.5 (0/31), nor are there excess resorption sites. Homozygous mutants are recovered at slightly lower than expected ratios at E3.5 and appear as dying morula. Mutants fail to hatch from the zona, never reaching a morphological blastocyst stage. RT-PCR indicates robust expression. Knock-in LacZ also shows robust expression in gastrulation stages. Additional information at websites.umass.edu/jmager/Ranbp2

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Ranbp2^{tm1.1(KOMP)Vlcg}	RAN binding protein 2; targeted mutation 1.1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Ranbp2^{tm1.1(KOMP)Vlcg}/Ranbp2^{tm1.1(KOMP)Vlcg}	C57BL/6N-Ranbp2^{tm1.1(KOMP)Vlcg}/MbpMmucd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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