Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Sepsecs^em1(IMPC)Tcp/Sepsecs^em1(IMPC)Tcp are recovered at expected Mendelian ratios at E7.5. Mutants show consistent phenotype including severe developmental delay as small egg cylinders, poorly organized extraembryonic tissues, and no Brachyury (T)-positive cells. RNA-seq data indicates robust maternal, zygotic and post-2-cell expression. Additional information at websites.umass.edu/jmager/Sepsecs

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Sepsecs^em1(IMPC)Tcp	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Associated
Genotypes

Allelic Composition	Genetic Background
Sepsecs^em1(IMPC)Tcp/Sepsecs^em1(IMPC)Tcp	C57BL/6NCrl-Sepsecs^em1(IMPC)Tcp/Cmmr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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