Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

Sepsecs^em1(IMPC)Tcp/Sepsecs^em1(IMPC)Tcp are recovered at expected Mendelian ratios at E7.5. Mutants show consistent phenotype including severe developmental delay as small egg cylinders, poorly organized extraembryonic tissues, and no Brachyury (T)-positive cells. RNA-seq data indicates robust maternal, zygotic and post-2-cell expression. Additional information at websites.umass.edu/jmager/Sepsecs

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Sepsecs^em1(IMPC)Tcp	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Associated
Genotypes

Allelic Composition	Genetic Background
Sepsecs^em1(IMPC)Tcp/Sepsecs^em1(IMPC)Tcp	C57BL/6NCrl-Sepsecs^em1(IMPC)Tcp/Cmmr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24