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Phenotype Image Detail
Image
Caption Osbpem1(IMPC)Tcp/Osbpem1(IMPC)Tcp embryos cannot be recovered at E7.5 (0/31), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as early blastocysts. Mutants hatch from the zona but form very irregular outgrowths with no evident inner cell mass colony or trophoblast giant cells. RNA-seq data indicates robust maternal, 2-cell, and post 8-cell expression. Additional information at websites.umass.edu/jmager/Osbp
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Osbpem1(IMPC)Tcp oxysterol binding protein; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Associated
Genotypes
Allelic Composition Genetic Background
Osbpem1(IMPC)Tcp/Osbpem1(IMPC)Tcp C57BL/6NCrl-Osbpem1(IMPC)Tcp/Cmmr

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory