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Phenotype Image Detail
Image
Caption Polr2jem1(IMPC)Bay/Polr2jem1(IMPC)Bay embryos cannot be recovered at E7.5 (0/27), nor are there excess reabsorption sites. Homozygous mutants are recovered at E3.5 in expected ratios and appear as dying morula or blastocysts. Mutants fail to hatch from the zona and are dead after 72hr in vitro outgrowth culture. RNA-seq data indicates robust expression. Additional information at websites.umass.edu/jmager/polr2j
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Polr2jem1(IMPC)Bay polymerase (RNA) II (DNA directed) polypeptide J; endonuclease-mediated mutation 1, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Polr2jem1(IMPC)Bay/Polr2jem1(IMPC)Bay C57BL/6NJ-Polr2jem1(IMPC)Bay/Mmmh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory