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Phenotype Image Detail
Image
Caption Srfbp1em1(IMPC)J/Srfbp1em1(IMPC)J embryos cannot be recovered at E7.5 (0/31), nor are there excess reabsorption sites. Homozygous mutants can be recovered at E3.5 and appear as compacting morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro outgrowth culture. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/srfbp1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Srfbp1em1(IMPC)J serum response factor binding protein 1; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Srfbp1em1(IMPC)J/Srfbp1em1(IMPC)J C57BL/6NJ-Srfbp1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory