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Phenotype Image Detail
Image
Caption Gpn1em1(IMPC)J/Gpn1em1(IMPC)J embryos cannot be recovered at E7.5 (0/30). Homozygous mutants can be recovered at E3.5 in expected ratios and appear as blastocysts. Mutants fail to hatch from the zona and are dead after 72hr in vitro outgrowth culture. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/gpn1
Copyright his image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Gpn1em1(IMPC)J GPN-loop GTPase 1; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Gpn1em1(IMPC)J/Gpn1em1(IMPC)J C57BL/6NJ-Gpn1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory