Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Apc^Min
Name:	APC, WNT signaling pathway regulator; multiple intestinal neoplasia
MGI ID:	MGI:1856318
Synonyms:	Apc^-, Apc^580S, Apc^delta850, Apc^Δ850, Min, Min-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Enhanced intestinal tumorigenesis in Apc^Min/Apc⁺ Mir10a^tm1.1Ahl/Mir10a^tm1.1Ahl mice	Apc^Min/Apc⁺ Mir10a^tm1.1Ahl/Mir10a^tm1.1Ahl	B6.Cg-Mir10a^tm1.1Ahl Apc^min
	Rab25^tm1Jrgo/Rab25^tm1Jrgo Apc^Min/Apc⁺ mice exhibit increased intestinal adenoma formation compared to Apc^Min/Apc⁺ mice	Apc^Min/Apc⁺	C57BL/6J-Apc^Min
		Apc^Min/Apc⁺ Rab25^tm1Jrgo/Rab25^tm1Jrgo	B6.Cg-Rab25^tm1Jrgo Apc^Min
	Rab25^tm1Jrgo/Rab25^tm1Jrgo Apc^Min/Apc⁺ mice exhibit increased colon adenoma formation compared to Apc^Min/Apc⁺ mice	Apc^Min/Apc⁺	C57BL/6J-Apc^Min
		Apc^Min/Apc⁺ Rab25^tm1Jrgo/Rab25^tm1Jrgo	B6.Cg-Rab25^tm1Jrgo Apc^Min
	Anterior head defects during embryonic development in Apc^Min/Apc^tm1Tno embryos and rescue of head defects by Ctnnb1^tm4.1Wbm/Ctnnb1⁺	Apc^Min/Apc^tm1Tno	involves: 129 * 129S4/SvJae * C57BL/6
		Apc^Min/Apc^tm1Tno Ctnnb1^tm4.1Wbm/Ctnnb1⁺	involves: 129 * 129P2/OlaHsd * 129S4/SvJae * C57BL/6
	Abnormal head structure development in Apc⁺/Apc^tm1Tno embryos and rescue by Ctnnb1^tm4.1Wbm/Ctnnb1⁺	Apc^Min/Apc^tm1Tno	involves: 129 * 129S4/SvJae * C57BL/6
		Apc^Min/Apc^tm1Tno Ctnnb1^tm4.1Wbm/Ctnnb1⁺	involves: 129 * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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