Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Lep^ob
Name:	leptin; obese
MGI ID:	MGI:1856424
Synonyms:	ob, ob/ob

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Adipose tissue macrophage infiltration in Fitm2^tm1.1DlsFitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? mice	Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/?	involves: 129S6/SvEvTac * C57BL/6J
	Reduced adiposity and unilocular lipid droplets in Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? Lep^ob/Lep^ob mice	Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Lep^ob/Lep^ob Tg(Fabp4-cre)1Rev/?	involves: 129S6/SvEvTac * C57BL/6J
	Increase in size of large lipid droplets in Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? brown adipose tissue	Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/?	involves: 129S6/SvEvTac * C57BL/6J
	Lep^ob/Lep^ob	Lep^ob/Lep^ob	B6.Cg-Lep^ob/J
	Lep^ob/Lep^ob	Lep^ob/Lep^ob	B6.Cg-Lep^ob/J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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