Phenotype Images associated with this Allele
Nomenclature
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Symbol:
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Ngfrtm1Jae
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Name:
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nerve growth factor receptor (TNFR superfamily, member 16);
targeted mutation 1, Rudolf Jaenisch
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MGI ID:
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MGI:1857226
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Synonyms:
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Ngfr-,
NGFRtm1Jac,
p75-,
p75e3-,
p75exonIII-,
p75(III)-,
p75-KO,
p75NGFR,
p75NTR-,
p75NTR-,
p75NTRexon3-null,
p75NTR/ExonIII-,
p75NTR KO
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Images for Allele
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Click images for details
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=448416) | Adult Ngftm1.1Blhe/Ngf+ mice exhibit dilated cardiomyopathy and fibrosis and this phentoype is rescued in Ngfrtm1Jae/Ngfrtm1Jae Ngftm1.1Blhe/Ngf+ mice | Ngftm1.1Blhe/Ngf+ | B6.Cg-Ngftm1.1Blhe | Ngftm1.1Blhe/Ngf+ Ngfrtm1Jae/Ngfrtm1Jae | B6.Cg-Ngftm1.1Blhe Ngfrtm1Jae |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=448420) | Abnormalities in the microvasculature of hearts from Ngftm1.1Blhe/Ngf+ mice and rescue of the phenotype in Ngfrtm1Jae/Ngfrtm1Jae Ngftm1.1Blhe/Ngf+ mice | Ngftm1.1Blhe/Ngf+ | B6.Cg-Ngftm1.1Blhe | Ngftm1.1Blhe/Ngf+ Ngfrtm1Jae/Ngfrtm1Jae | B6.Cg-Ngftm1.1Blhe Ngfrtm1Jae |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=448422) | Reduced infarct size in Ngfrtm1Jae/Ngfrtm1Jae mice after cardiac ischemia-reperfusion surgery | Ngfrtm1Jae/Ngfrtm1Jae | B6.129S4-Ngfrtm1Jae/J |
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