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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ngfrtm1Jae
Name: nerve growth factor receptor (TNFR superfamily, member 16); targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:1857226
Synonyms: Ngfr-, NGFRtm1Jac, p75-, p75e3-, p75exonIII-, p75(III)-, p75-KO, p75NGFR, p75NTR-, p75NTR-, p75NTRexon3-null, p75NTR/ExonIII-, p75NTR KO
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Adult Ngftm1.1Blhe/Ngf+ mice exhibit dilated cardiomyopathy and fibrosis and this phentoype is rescued in Ngfrtm1Jae/Ngfrtm1Jae Ngftm1.1Blhe/Ngf+ miceNgftm1.1Blhe/Ngf+B6.Cg-Ngftm1.1Blhe
Ngftm1.1Blhe/Ngf+
Ngfrtm1Jae/Ngfrtm1Jae
B6.Cg-Ngftm1.1Blhe Ngfrtm1Jae
Abnormalities in the microvasculature of hearts from Ngftm1.1Blhe/Ngf+ mice and rescue of the phenotype in Ngfrtm1Jae/Ngfrtm1Jae Ngftm1.1Blhe/Ngf+ miceNgftm1.1Blhe/Ngf+B6.Cg-Ngftm1.1Blhe
Ngftm1.1Blhe/Ngf+
Ngfrtm1Jae/Ngfrtm1Jae
B6.Cg-Ngftm1.1Blhe Ngfrtm1Jae
Reduced infarct size in Ngfrtm1Jae/Ngfrtm1Jae mice after cardiac ischemia-reperfusion surgeryNgfrtm1Jae/Ngfrtm1JaeB6.129S4-Ngfrtm1Jae/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory